New York Giants at Buffalo Bills: Predictions, picks and odds for NFL … – USA TODAY

The Buffalo Bills (3-2) return stateside to take on the New York Giants (1-4) at home for a primetime Sunday game.
The Bills lost more than the game last week when they fell to the Jacksonville Jaguars 25-20 in London. Star linebacker Matt Milano injured his leg and could be out for the season. Josh Allen is fifth in the league with 1,407 passing yards and in a four-way tie for second with 11 touchdowns.
The Giants finally forced their first turnover of the season last week when De’Von Achane fumbled and they intercepted Tua Tagovailoa twice. But the defensive effort wasn’t enough as they fell to the Miami Dolphins 31-16. Daniel Jones suffered a neck injury in the game and New York is still monitoring the health of running back Saquon Barkley.
The two teams last faced off in 2019 when the Bills intercepted Eli Manning twice and won 28-14.
PROP TALK: These are the best prop bets for NFL games this week
NFL STATS CENTRAL: The latest NFL scores, schedules, odds, stats and more.
The Bills are favorites to defeat the Giants, according to the BetMGM NFL odds. Looking to wager? Check out the best mobile sports betting apps offering NFL betting promos in 2023.
Not interested in this game? Our guide to the NFL betting odds, picks and spreads has you covered with Thursday Night Football odds, Sunday Night Football odds and/or Monday Night Football odds.
If you’re new to sports betting, don’t worry. We have tips for beginners on how to place bet online. And USA TODAY readers can claim exclusive promos and bonus codes with the online sportsbooks and sports betting sites.
NFL Week 5 winners, losers:Mike McCarthy, Cowboys get exposed by 49ers
Chiefs vs. Broncos | Titans vs. Ravens | Falcons vs. Commanders | Bears vs. Vikings | Bengals vs. Seahawks | Browns vs. 49ers | Texans vs. Saints | Jaguars vs. Colts | Dolphins vs. Panthers | Raiders vs. Patriots | Buccaneers vs. Lions | Rams vs. Cardinals | Jets vs. Eagles | Bills vs. Giants | Chargers vs. Cowboys
The Bills already lost to the Jets in primetime. It’s hard to imagine Buffalo losing to another in-state rival under the bright lights. Aside from a fourth-quarter rally in Arizona, the Giants have been outplayed in 19 quarters to start the season.
The Giants are missing Saquon Barkley badly. Getting Darren Waller more involved has helped and Tyrod Taylor isn’t given enough credit for his abilities, so it won’t be completely game-over if he plays instead of Daniel Jones. The Bills have something to prove and are playing at home, but are also without one of their star players in linebacker Matt Milano. Buffalo will win easily, but probably won’t cover the monster spread.
Josh Allen and the Bills have a “get right” game at home, after losing to the Jaguars in London last week. They should blow out the floundering Giants, who could be without starting quarterback Daniel Jones (neck) while running back Saquon Barkley’s return from an ankle injury might be imminent. 
You can view the full list of USA TODAY’s NFL expert predictions here.
32 things we learned in NFL Week 5:Ravens, Patriots spiral as other teams get right
Gannett may earn revenue from sports betting operators for audience referrals to betting services. Sports betting operators have no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. Terms apply, see operator site for Terms and Conditions. If you or someone you know has a gambling problem, help is available. Call the National Council on Problem Gambling 24/7 at 1-800-GAMBLER (NJ, OH), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA), 1-800-9-WITH-IT (IN). Must be 21 or older to gamble. Sports betting and gambling are not legal in all locations. Be sure to comply with laws applicable where you reside.

source