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Houston Texans vs Indianapolis Colts picks, predictions, odds for NFL Week 13 recreation Sunday – azcentral.com and The Arizona Republic

November 26, 2025
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The Houston Texans and Indianapolis Colts play on Sunday, Nov. 30, on the Colts’ Lucas Oil Stadium in a recreation on the NFL Week 13 schedule.
Which group will win the NFL Week 13 game?
Try these NFL Week 13 picks and NFL Week 13 predictions for the sport, which can be seen at 11 a.m. MST on CBS (stream with FUBO).
The Colts are a 4.5-point favourite over the Texans in NFL Week 13 odds for the sport, courtesy of BetMGM Sportsbook.
Indianapolis is -220 on the moneyline, whereas Houston is +185. The over/below (level whole) is about at 44.5 factors.
NFL Week 13 picks: Packers at Lions | Chiefs at Cowboys | Bengals at Ravens | Bears at Eagles | Rams at Panthers | 49ers at Browns | Texans at Colts | Saints at Dolphins | Falcons at Jets | Cardinals at Buccaneers | Jaguars at Titans | Vikings at Seahawks | Raiders at Chargers | Bills at Steelers | Broncos at Commanders | Giants at Patriots | The Republic’s score predictions
Jeremy Cluff writes: “The Texans’ protection offers them a preventing likelihood in each recreation, however the Colts are an ideal 6-0 at dwelling this season. Jonathan Taylor will discover a method to break some large runs for Indianapolis.”
Invoice Speros writes: “The 8-3 Colts bought a full dose of Mahomes Magic Sunday. Indy – with some assist from Park Avenue – blew a 20-9 lead at Kansas Metropolis earlier than shedding 23-20 in additional time. Indiana Jones & Firm should present they’re for actual with a bounce-back win in opposition to a troublesome divisional opponent this week. The 6-5 Texans enter this recreation as winners of three straight, together with two in opposition to AFC South foes. The Texans are winless on the street in opposition to successful groups. The Colts have lined in 7 of their previous 8 AFC South video games. Somebody’s getting uncovered this week.”
The location’s components predicts that the Colts will win the NFL Week 13 recreation in opposition to the Texans.
The location offers the Texans a 36.5% shot at successful the NFL Week 13 recreation, with the remaining proportion accounting for a tie.
It writes: “After intensive simulations, our mannequin offers the Texans a win chance of 58%, whereas the Colts have a win chance of 42%.”
Nick Hennion writes: “Based mostly on Houston’s sturdy defensive document this season and the Colts’ enhancing defensive document, my Colts vs Texans prediction is the Complete Beneath 44.5 Factors (-110). Anytime I see a complete above key numbers with DeMeco Ryans, I’m inclined to foretell an below. In his teaching profession, Ryans is 24-4 to the below when the entire closes above 42 factors. This season, he’s 4-0 in such conditions.”
NFL’s highest paid gamers in 2025: Quarterbacks | Running backs | Wide receivers | Tight ends | Offensive linemen | D-linemen | Cornerbacks | Safeties | Linebackers | Edge rushers | Highest paid NFL players: Overall | By position | By team
Attain Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Observe him on X, previously Twitter @Jeremy_Cluff.
Help native journalism: Subscribe to azcentral.com right this moment. Join azcentral Preps Now. And be sure you subscribe to our daily sports newsletters so you do not miss a factor.
Our group of savvy editors independently handpicks all suggestions. If you are going to buy by way of our hyperlinks, the USA Right now Community could earn a fee. Costs had been correct on the time of publication however could change.
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