NFL Week 12 video games: Odds and professional predictions for each matchup – USA At present

NFL season is formally in Week 12. This week options 5 video games between groups which have a minimum of a .500 report.
The 5-5 Kansas City Chiefs desperately want a win after they host the 8-2 Indianapolis Colts. Two of one of the best groups within the NFC meet up in primetime on Sunday evening when the 6-4 Tampa Bay Buccaneers face the 8-2 Los Angeles Rams.  
There are sure to be loads of shut contests this week. There have been 43 video games with a game-winning rating within the remaining two minutes of regulation or in extra time this season, the most-ever by way of Week 11, by way of NFL Analysis.
Here’s a have a look at picks and predictions for all the Week 12 video games on the 2025 NFL schedule.
Odds courtesy of BetMGM.
Tyler Dragon, USA TODAY: Payments 27, Texans 20
C.J. Stroud continues to be in concussion protocol. The Texans defensive position ought to make life troublesome for Josh Allen, however the Payments are the extra full staff are a making an attempt to maintain tempo with the Patriots. I imagine Buffalo wins this one on the highway.
Jeremy Cluff, Arizona Republic: Payments 27, Texans 20
“The Texans have allowed an NFL-best 163 factors, however they face a Payments staff that simply had Josh Allen rating six touchdowns and put up 44 factors. Buffalo will be capable to outscore Houston.”
Bill Bender, Sporting News: Payments 28, Texans 17 
“Will C.J. Stroud (concussion) return for the Texans? Houston is 2-2 S/U at dwelling, however these losses to Denver and Tampa Bay have been by a mixed whole of 4 factors. Buffalo is 2-2 S/U on the highway. Josh Allen is coming off a six-TD efficiency. That is go-time for the Bills in the event that they wish to catch the Patriots within the AFC East.”
Tyler Dragon, USA TODAY: Steelers 25, Bears 24
Ben Johnson deserves coach of the yr consideration with how he’s helped flip across the Bears. Johnson’s helped Caleb Williams play with extra construction throughout the offense. Nevertheless, I feel the mixture of T.J. Watt and Alex Highsmith will disrupt Chicago’s offensive assault. Plus, DK Metcalf and Pittsburgh’s tight ends are going to make sufficient performs on offense.
Jeremy Cluff, Arizona Republic: Bears 24, Steelers 23
“Will Aaron Rodgers or Mason Rudolph begin for the Steelers? Will it matter? Caleb Williams and the Bears will win a fourth straight shut sport.”
Bill Bender, Sporting News: Bears 20, Steelers 19
“The Bears haven’t turned the ball over in these three wins – could be primed for one thing extra, particularly in the event that they power two or extra turnovers from Steelers quarterback Mason Rudolph. It is a powerful decide, however we’ll stick to Chicago.”
Tyler Dragon, USA TODAY: Patriots 26, Bengals 20
TreVeyon Henderson is coming off a three-touchdown sport. He’s added some explosiveness to New England’s offense. Stefon Diggs is actually beginning to construct a rapport with Drake Maye who’s rising as a star. The Bengals don’t have the protection to cease the Patriots offense.
Jeremy Cluff, Arizona Republic: Patriots 31, Bengals 20
“The Patriots are 5-0 on the highway this season. They are going to be 6-0 after Drake Maye and New England beat the Bengals in Cincinnati.”
Bill Bender, Sporting News: Patriots 30, Bengals 20
“The Patriots are on an eight-game profitable streak, and the Bengals haven’t pressured a turnover of their final three losses. It is a dangerous protection made worse when Trey Hendrickson just isn’t on the sector. TreVeyon Henderson – a former Ohio State working again with 4 dashing TDs the final two weeks – might have a monster sport right here. The Pats are 3-0-1 ATS when favored by greater than 5 factors.”
Tyler Dragon, USA TODAY: Lions 28, Giants 20
The Lions offensive line versus the Giants defensive position is a matchup to observe. However Detroit has a number of methods to win towards an inferior Giants membership. The Lions roar on this one.
Jeremy Cluff, Arizona Republic: Lions 33, Giants 17
“Jared Goff and the Lions haven’t misplaced back-to-back video games all season. They don’t seem to be going to start out right here. Detroit will rebound with an enormous offensive efficiency at dwelling.”
Bill Bender, Sporting News: Lions 31, Giants 16
“The Lions are 3-1 at dwelling, and so they received these video games by a mean margin of 23.3 factors per sport. Jameis Winston had two turnovers within the loss to the Packers in Week 12. Detroit will get on observe in a convincing trend right here to prepare for the rematch with Inexperienced Bay on Thanksgiving.”
Tyler Dragon, USA TODAY: Packers 26, Vikings 17
The Vikings swept the season collection final yr. I feel the Packers return the favor this season. Inexperienced Bay’s offense has struggled in current weeks, however the Packers ought to have some benefits vertically.
Jeremy Cluff, Arizona Republic: Packers 21, Vikings 20
“The accidents are beginning to take a toll on the Packers, however Jordan Love will make some massive throws late to assist Inexperienced Bay edge Minnesota in an NFC North thriller.”
Bill Bender, Sporting News: Packers 23, Vikings 19 
“The Vikings are in desperation mode right here after a heartbreaking loss to the Bears. JJ McCarthy didn’t take a sack within the loss to Chicago, however he has struggled with accuracy (50.5%) the final three weeks. 4 of Minnesota’s 5 highway video games have been determined by one rating. Will the Packers lose a 3rd straight sport at Lambeau Area?”
Tyler Dragon, USA TODAY: Seahawks 28, Titans 17
Let’s face it, the Titans are rebuilding and lack expertise exterior of constructing blocks, Cam Ward and Jeffery Simmons. The Seahawks are one of many high groups within the NFL. Mike Macdonald deserves coach of the yr consideration.
Jeremy Cluff, Arizona Republic: Seahawks 27, Titans 14
“We do not see Sam Darnold throwing 4 interceptions on this sport and Seattle nearly beat the Los Angeles Rams final week when he did.”
Bill Bender, Sporting News: Seahawks 28, Titans 19
“Is that this a possible emotional letdown spot for the Seahawks coming off the loss to the Rams? The Titans have misplaced consecutive one-score video games, and the shortcoming to run the soccer with a league-worst 78.9 dashing yards per sport continues to be an issue. That is a variety of factors for a highway staff to cowl.”
Tyler Dragon, USA TODAY: Chiefs 26, Colts 24
Jonathan Taylor and Daniel Jones are MVP candidates, however I it is a must-win sport for the Chiefs. The AFC West could be out of attain for Kansas Metropolis, however a playoff berth isn’t.
Jeremy Cluff, Arizona Republic: Chiefs 28, Colts 24
“The Chiefs are a significantly better staff at dwelling (4-1) than on the highway (1-4). It is a must-win sport for Kansas Metropolis towards an Indianapolis staff coming off a bye. Patrick Mahomes and firm will get it executed.”
Bill Bender, Sporting News: Chiefs 27, Colts 20 
“The Chiefs are .500 and face the Colts coming off a bye week. Kansas Metropolis is 0-5 S/U in one-score video games this yr – a nasty omen towards Indianapolis. The Colts are 3-2 S/U in one-score video games. The Chiefs permit 100 dashing yards per sport. How a lot will they provide as much as MVP candidate Jonathan Taylor? That’s going to be the important thing at Arrowhead Stadium.”
Tyler Dragon, USA TODAY: Ravens 28, Jets 17
The Ravens have received 4 straight video games and are starting to resemble the staff many picked to symbolize the AFC in Tremendous Bowl 60. The Jets are within the infancy levels of a rebuild after gutting their staff on the commerce deadline.
Jeremy Cluff, Arizona Republic: Ravens 30, Jets 14
“The Ravens wanted to rally to win their fourth straight sport final week. Lamar Jackson and firm will not have to rally on this sport. Baltimore will cruise to a fifth straight win.”
Bill Bender, Sporting News: Ravens 35, Jets 17
“Is that this blowout ready to occur? New York has truly performed higher on the highway – the place their three losses are by a mean of seven factors per sport. It is simply troublesome to entertain an upset figuring out the Jets have a passing assault that averages a league-worst 139.9 yards per sport and benched Justin Fields. Lamar Jackson will get the Ravens’ offense going towards a Jets’ protection that has pressured one turnover all season.”
Tyler Dragon, USA TODAY: Browns 17-16
The is a decide ‘em sport between two dangerous groups. Anyone has to win, proper (perhaps)? The Browns have one of many NFL’s high defensive models. I feel Myles Garrett and Cleveland’s protection power a pair turnovers that result in a victory.
Jeremy Cluff, Arizona Republic: Raiders 20, Browns 17
“The Browns will probably be beginning a rookie QB on the highway. Benefit: Las Vegas. However not by a lot with Cleveland’s protection maintaining it shut.”
Bill Bender, Sporting News: Raiders 20, Browns 19
“Will Shedeur Sanders begin? That is one of many burning questions for 2 groups that rank within the backside 5 in scoring offense. Myles Garrett — who had 4 sacks in Week 10 — and Maxx Crosby – who has heated up at dwelling – are going to be key gamers in what ought to be an unsightly matchup. The Raiders are 3-0 S/U towards the Browns since shifting to Las Vegas.”
Tyler Dragon, USA TODAY: Jaguars 26, Cardinals 20
The Jaguars are coming off an enormous Week 11 win. Jacksonville carries that momentum into Arizona. I’d’ve beloved to see Travis Hunter matched up towards Marvin Harrison Jr. on this sport.
Jeremy Cluff, Arizona Republic: Jaguars 24, Cardinals 20
“The Cardinals have given up 85 factors of their final two video games. They will not quit that many to Trevor Lawrence and the Jaguars, however they’ll quit greater than they rating.”
Bill Bender, Sporting News: Jaguars 26, Cardinals 21
“The Cardinals have allowed a mean of 42.5 factors the final two weeks. Jacksonville has scored 29 or extra factors in its final three video games and is coming off a blowout victory towards the Chargers. Travis Etienne and Bhayshul Tuten towards a middle-of-the-pack Arizona run protection. That is the Jaguars’ third West Coast journey this season – and they’re 2-0 S/U.”
Tyler Dragon, USA TODAY: Eagles 26, Cowboys 21
The Eagles swept the season collection towards the Cowboys final season. Philadelphia is sure to do it once more this yr. I count on Saquon Barkley and A.J. Brown to have massive performances towards a leaky however improved Cowboys protection, not like the Week 1 matchup.
Jeremy Cluff, Arizona Republic: Eagles 30, Cowboys 23
“The Cowboys are a significantly better staff at dwelling than on the highway, however are coming off a brief week for this sport. We belief Philadelphia’s protection extra.”
Bill Bender, Sporting News: Eagles 27, Cowboys 17
“Preserve doubting the Eagles at your individual peril. Philadelphia allowed 16 whole factors in victories towards the Packers and Lions. Protection is the identification of this staff. Jalen Hurts is 1-3 S/U in 4 profession begins at AT&T Stadium, however he ought to be capable to management the sport towards Dallas’ protection. The Eagles have an opportunity to make it 4 in a row within the collection.” 
Tyler Dragon, USA TODAY: Falcons 20, Saints 17
Bijan Robinson and Atlanta’s run sport have some benefits towards the Saints protection. Kirk Cousins’ purpose ought to be handy the ball off to Robinson and keep away from pricey errors. Losers of 5 straight video games, the Falcons actually need this sport in the event that they wish to hold their season afloat.
Jeremy Cluff, Arizona Republic: Saints 21, Falcons 20
“The Falcons are favored, however the Saints are coming off a bye week and Tyler Shough had further time to organize for this begin. New Orleans will win a second straight sport and hand Atlanta a sixth straight loss.”
Bill Bender, Sporting News: Falcons 20, Saints 17 
“The Saints had a bye week, and the Falcons are caught in a six-game shedding streak that has peaked with extra time losses every of the final two weeks towards the Colts and Panthers. Tyler Shough has taken three sacks or much less in his three begins, however the Saints are averaging simply 10 factors per sport in these matchups. New Orleans has received the final three dwelling conferences. Kirk Cousins breaks the streak.”
Tyler Dragon, USA TODAY: Rams 28, Bucs 25
The Rams are a contender, however they could simply be the highest staff within the convention. A win towards the Seahawks final week, adopted by a victory towards Tampa Bay this week would ship an announcement to the remainder of the NFL.
Jeremy Cluff, Arizona Republic: Rams 28, Buccaneers 20
“Matthew Stafford might not be a twin risk like Josh Allen, however he’ll be capable to decide aside Tampa Bay’s secondary in main Los Angeles to a sixth straight win.”
Bill Bender, Sporting News: Rams 34, Buccaneers 28 
“What can the Buccaneers do to decelerate Matthew Stafford – who has 27 TDs, two interceptions and a 112.7 passer ranking? Stafford has but to throw an interception at dwelling. Tampa Bay is 0-2 ATS as an underdog of six factors or extra. Will Baker Mayfield assist Tampa Bay keep away from a 3rd consecutive loss?”
Tyler Dragon, USA TODAY: 49ers 26, Panthers 21
Kyle Shanahan deserves a variety of credit score for maintaining the 49ers’ season afloat regardless of a depleted roster. Brock Purdy is again behind middle, and he nonetheless has weapons Christian McCaffrey and George Kittle.
Jeremy Cluff, Arizona Republic: 49ers 24, Panthers 21
“Bryce Younger and the Panthers have been a shock within the NFC, however it might actually be a shock to us if Carolina upset Brock Purdy and San Francisco on the highway.”
Bill Bender, Sporting News: 49ers 27, Panthers 21
“The Panthers could be the most-interesting boom-or-bust staff within the NFL proper now. Carolina has received its final two highway video games at Inexperienced Bay and Atlanta. Brock Purdy was environment friendly in his return for the 49ers. San Francisco is 3-2 ATS as a favourite this yr, however Bryce Younger continues to enhance on the highway.”
Comply with USA TODAY Sports activities’ Tyler Dragon on X @TheTylerDragon.
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