NFL Week 12 video games: Odds and skilled predictions for each matchup – USA Immediately

NFL season is formally in Week 12. This week options 5 video games between groups which have at the very least a .500 file.
The 5-5 Kansas City Chiefs desperately want a win once they host the 8-2 Indianapolis Colts. Two of the perfect groups within the NFC meet up in primetime on Sunday night time when the 6-4 Tampa Bay Buccaneers face the 8-2 Los Angeles Rams.  
There are sure to be loads of shut contests this week. There have been 43 video games with a game-winning rating within the remaining two minutes of regulation or in extra time this season, the most-ever via Week 11, through NFL Analysis.
Here’s a have a look at picks and predictions for all the Week 12 video games on the 2025 NFL schedule.
Odds courtesy of BetMGM.
Tyler Dragon, USA TODAY: Payments 27, Texans 20
C.J. Stroud remains to be in concussion protocol. The Texans defensive position ought to make life tough for Josh Allen, however the Payments are the extra full crew are a attempting to maintain tempo with the Patriots. I consider Buffalo wins this one on the street.
Jeremy Cluff, Arizona Republic: Payments 27, Texans 20
“The Texans have allowed an NFL-best 163 factors, however they face a Payments crew that simply had Josh Allen rating six touchdowns and put up 44 factors. Buffalo will have the ability to outscore Houston.”
Bill Bender, Sporting News: Payments 28, Texans 17 
“Will C.J. Stroud (concussion) return for the Texans? Houston is 2-2 S/U at house, however these losses to Denver and Tampa Bay have been by a mixed whole of 4 factors. Buffalo is 2-2 S/U on the street. Josh Allen is coming off a six-TD efficiency. That is go-time for the Bills in the event that they need to catch the Patriots within the AFC East.”
Tyler Dragon, USA TODAY: Steelers 25, Bears 24
Ben Johnson deserves coach of the 12 months consideration with how he’s helped flip across the Bears. Johnson’s helped Caleb Williams play with extra construction throughout the offense. Nonetheless, I believe the mix of T.J. Watt and Alex Highsmith will disrupt Chicago’s offensive assault. Plus, DK Metcalf and Pittsburgh’s tight ends are going to make sufficient performs on offense.
Jeremy Cluff, Arizona Republic: Bears 24, Steelers 23
“Will Aaron Rodgers or Mason Rudolph begin for the Steelers? Will it matter? Caleb Williams and the Bears will win a fourth straight shut recreation.”
Bill Bender, Sporting News: Bears 20, Steelers 19
“The Bears haven’t turned the ball over in these three wins – is perhaps primed for one thing extra, particularly in the event that they drive two or extra turnovers from Steelers quarterback Mason Rudolph. This can be a powerful choose, however we are going to follow Chicago.”
Tyler Dragon, USA TODAY: Patriots 26, Bengals 20
TreVeyon Henderson is coming off a three-touchdown recreation. He’s added some explosiveness to New England’s offense. Stefon Diggs is admittedly beginning to construct a rapport with Drake Maye who’s rising as a star. The Bengals don’t have the protection to cease the Patriots offense.
Jeremy Cluff, Arizona Republic: Patriots 31, Bengals 20
“The Patriots are 5-0 on the street this season. They are going to be 6-0 after Drake Maye and New England beat the Bengals in Cincinnati.”
Bill Bender, Sporting News: Patriots 30, Bengals 20
“The Patriots are on an eight-game profitable streak, and the Bengals haven’t pressured a turnover of their final three losses. It is a unhealthy protection made worse when Trey Hendrickson shouldn’t be on the sector. TreVeyon Henderson – a former Ohio State working again with 4 speeding TDs the final two weeks – may have a monster recreation right here. The Pats are 3-0-1 ATS when favored by greater than 5 factors.”
Tyler Dragon, USA TODAY: Lions 28, Giants 20
The Lions offensive line versus the Giants defensive position is a matchup to observe. However Detroit has a number of methods to win in opposition to an inferior Giants membership. The Lions roar on this one.
Jeremy Cluff, Arizona Republic: Lions 33, Giants 17
“Jared Goff and the Lions haven’t misplaced back-to-back video games all season. They aren’t going to start out right here. Detroit will rebound with a giant offensive efficiency at house.”
Bill Bender, Sporting News: Lions 31, Giants 16
“The Lions are 3-1 at house, and so they gained these video games by a mean margin of 23.3 factors per recreation. Jameis Winston had two turnovers within the loss to the Packers in Week 12. Detroit will get on monitor in a convincing style right here to prepare for the rematch with Inexperienced Bay on Thanksgiving.”
Tyler Dragon, USA TODAY: Packers 26, Vikings 17
The Vikings swept the season collection final 12 months. I believe the Packers return the favor this season. Inexperienced Bay’s offense has struggled in latest weeks, however the Packers ought to have some benefits vertically.
Jeremy Cluff, Arizona Republic: Packers 21, Vikings 20
“The accidents are beginning to take a toll on the Packers, however Jordan Love will make some huge throws late to assist Inexperienced Bay edge Minnesota in an NFC North thriller.”
Bill Bender, Sporting News: Packers 23, Vikings 19 
“The Vikings are in desperation mode right here after a heartbreaking loss to the Bears. JJ McCarthy didn’t take a sack within the loss to Chicago, however he has struggled with accuracy (50.5%) the final three weeks. 4 of Minnesota’s 5 street video games have been determined by one rating. Will the Packers lose a 3rd straight recreation at Lambeau Area?”
Tyler Dragon, USA TODAY: Seahawks 28, Titans 17
Let’s face it, the Titans are rebuilding and lack expertise exterior of constructing blocks, Cam Ward and Jeffery Simmons. The Seahawks are one of many prime groups within the NFL. Mike Macdonald deserves coach of the 12 months consideration.
Jeremy Cluff, Arizona Republic: Seahawks 27, Titans 14
“We do not see Sam Darnold throwing 4 interceptions on this recreation and Seattle nearly beat the Los Angeles Rams final week when he did.”
Bill Bender, Sporting News: Seahawks 28, Titans 19
“Is that this a possible emotional letdown spot for the Seahawks coming off the loss to the Rams? The Titans have misplaced consecutive one-score video games, and the shortcoming to run the soccer with a league-worst 78.9 speeding yards per recreation continues to be an issue. That is a number of factors for a street crew to cowl.”
Tyler Dragon, USA TODAY: Chiefs 26, Colts 24
Jonathan Taylor and Daniel Jones are MVP candidates, however I this can be a must-win recreation for the Chiefs. The AFC West is perhaps out of attain for Kansas Metropolis, however a playoff berth isn’t.
Jeremy Cluff, Arizona Republic: Chiefs 28, Colts 24
“The Chiefs are a significantly better crew at house (4-1) than on the street (1-4). This can be a must-win recreation for Kansas Metropolis in opposition to an Indianapolis crew coming off a bye. Patrick Mahomes and firm will get it achieved.”
Bill Bender, Sporting News: Chiefs 27, Colts 20 
“The Chiefs are .500 and face the Colts coming off a bye week. Kansas Metropolis is 0-5 S/U in one-score video games this 12 months – a foul omen in opposition to Indianapolis. The Colts are 3-2 S/U in one-score video games. The Chiefs permit 100 speeding yards per recreation. How a lot will they provide as much as MVP candidate Jonathan Taylor? That’s going to be the important thing at Arrowhead Stadium.”
Tyler Dragon, USA TODAY: Ravens 28, Jets 17
The Ravens have gained 4 straight video games and are starting to resemble the crew many picked to characterize the AFC in Tremendous Bowl 60. The Jets are within the infancy phases of a rebuild after gutting their crew on the commerce deadline.
Jeremy Cluff, Arizona Republic: Ravens 30, Jets 14
“The Ravens wanted to rally to win their fourth straight recreation final week. Lamar Jackson and firm will not have to rally on this recreation. Baltimore will cruise to a fifth straight win.”
Bill Bender, Sporting News: Ravens 35, Jets 17
“Is that this blowout ready to occur? New York has truly performed higher on the street – the place their three losses are by a mean of seven factors per recreation. It is simply tough to entertain an upset figuring out the Jets have a passing assault that averages a league-worst 139.9 yards per recreation and benched Justin Fields. Lamar Jackson will get the Ravens’ offense going in opposition to a Jets’ protection that has pressured one turnover all season.”
Tyler Dragon, USA TODAY: Browns 17-16
The is a choose ‘em recreation between two unhealthy groups. Anyone has to win, proper (possibly)? The Browns have one of many NFL’s prime defensive items. I believe Myles Garrett and Cleveland’s protection drive a pair turnovers that result in a victory.
Jeremy Cluff, Arizona Republic: Raiders 20, Browns 17
“The Browns will likely be beginning a rookie QB on the street. Benefit: Las Vegas. However not by a lot with Cleveland’s protection retaining it shut.”
Bill Bender, Sporting News: Raiders 20, Browns 19
“Will Shedeur Sanders begin? That is one of many burning questions for 2 groups that rank within the backside 5 in scoring offense. Myles Garrett — who had 4 sacks in Week 10 — and Maxx Crosby – who has heated up at house – are going to be key gamers in what needs to be an unsightly matchup. The Raiders are 3-0 S/U in opposition to the Browns since shifting to Las Vegas.”
Tyler Dragon, USA TODAY: Jaguars 26, Cardinals 20
The Jaguars are coming off a giant Week 11 win. Jacksonville carries that momentum into Arizona. I’d’ve beloved to see Travis Hunter matched up in opposition to Marvin Harrison Jr. on this recreation.
Jeremy Cluff, Arizona Republic: Jaguars 24, Cardinals 20
“The Cardinals have given up 85 factors of their final two video games. They will not hand over that many to Trevor Lawrence and the Jaguars, however they may hand over greater than they rating.”
Bill Bender, Sporting News: Jaguars 26, Cardinals 21
“The Cardinals have allowed a mean of 42.5 factors the final two weeks. Jacksonville has scored 29 or extra factors in its final three video games and is coming off a blowout victory in opposition to the Chargers. Travis Etienne and Bhayshul Tuten in opposition to a middle-of-the-pack Arizona run protection. That is the Jaguars’ third West Coast journey this season – and they’re 2-0 S/U.”
Tyler Dragon, USA TODAY: Eagles 26, Cowboys 21
The Eagles swept the season collection in opposition to the Cowboys final season. Philadelphia is sure to do it once more this 12 months. I anticipate Saquon Barkley and A.J. Brown to have huge performances in opposition to a leaky however improved Cowboys protection, in contrast to the Week 1 matchup.
Jeremy Cluff, Arizona Republic: Eagles 30, Cowboys 23
“The Cowboys are a significantly better crew at house than on the street, however are coming off a brief week for this recreation. We belief Philadelphia’s protection extra.”
Bill Bender, Sporting News: Eagles 27, Cowboys 17
“Hold doubting the Eagles at your individual peril. Philadelphia allowed 16 whole factors in victories in opposition to the Packers and Lions. Protection is the id of this crew. Jalen Hurts is 1-3 S/U in 4 profession begins at AT&T Stadium, however he ought to have the ability to management the sport in opposition to Dallas’ protection. The Eagles have an opportunity to make it 4 in a row within the collection.” 
Tyler Dragon, USA TODAY: Falcons 20, Saints 17
Bijan Robinson and Atlanta’s run recreation have some benefits in opposition to the Saints protection. Kirk Cousins’ purpose needs to be at hand the ball off to Robinson and keep away from expensive errors. Losers of 5 straight video games, the Falcons actually need this recreation in the event that they need to maintain their season afloat.
Jeremy Cluff, Arizona Republic: Saints 21, Falcons 20
“The Falcons are favored, however the Saints are coming off a bye week and Tyler Shough had additional time to arrange for this begin. New Orleans will win a second straight recreation and hand Atlanta a sixth straight loss.”
Bill Bender, Sporting News: Falcons 20, Saints 17 
“The Saints had a bye week, and the Falcons are caught in a six-game shedding streak that has peaked with extra time losses every of the final two weeks in opposition to the Colts and Panthers. Tyler Shough has taken three sacks or much less in his three begins, however the Saints are averaging simply 10 factors per recreation in these matchups. New Orleans has gained the final three house conferences. Kirk Cousins breaks the streak.”
Tyler Dragon, USA TODAY: Rams 28, Bucs 25
The Rams are a contender, however they may simply be the highest crew within the convention. A win in opposition to the Seahawks final week, adopted by a victory in opposition to Tampa Bay this week would ship an announcement to the remainder of the NFL.
Jeremy Cluff, Arizona Republic: Rams 28, Buccaneers 20
“Matthew Stafford might not be a twin risk like Josh Allen, however he’ll have the ability to choose aside Tampa Bay’s secondary in main Los Angeles to a sixth straight win.”
Bill Bender, Sporting News: Rams 34, Buccaneers 28 
“What can the Buccaneers do to decelerate Matthew Stafford – who has 27 TDs, two interceptions and a 112.7 passer ranking? Stafford has but to throw an interception at house. Tampa Bay is 0-2 ATS as an underdog of six factors or extra. Will Baker Mayfield assist Tampa Bay keep away from a 3rd consecutive loss?”
Tyler Dragon, USA TODAY: 49ers 26, Panthers 21
Kyle Shanahan deserves a number of credit score for retaining the 49ers’ season afloat regardless of a depleted roster. Brock Purdy is again behind middle, and he nonetheless has weapons Christian McCaffrey and George Kittle.
Jeremy Cluff, Arizona Republic: 49ers 24, Panthers 21
“Bryce Younger and the Panthers have been a shock within the NFC, however it will actually be a shock to us if Carolina upset Brock Purdy and San Francisco on the street.”
Bill Bender, Sporting News: 49ers 27, Panthers 21
“The Panthers is perhaps the most-interesting boom-or-bust crew within the NFL proper now. Carolina has gained its final two street video games at Inexperienced Bay and Atlanta. Brock Purdy was environment friendly in his return for the 49ers. San Francisco is 3-2 ATS as a favourite this 12 months, however Bryce Younger continues to enhance on the street.”
Observe USA TODAY Sports activities’ Tyler Dragon on X @TheTylerDragon.
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